ABSTRACT
Dopamine, norepinephrine, 5-hydroxytryptamine, and 5-hydroxyndoleacetic acid concentrations were measured in human seminal plasma and follicular fluid of healthy fertile individuals and in seminal plasma of azoospermic patients. All these substances were unevenly distributed in the male and female reproductive tract fluids. The highest monoamine (MA) concentration was observed for azoospermic seminal plasma followed by normal seminal plasma and follicular fluid. The differences in MA content were statistically significant. The occurrence of MA in human follicular fluid supports the suggestion of several authors that MA are involved in the regulation of the acquisition of the fertilizing ability of the sperm in female reproductive tract. However, the presence and uneven distribution of each MA in male and female fluids testify the complexity of the MA function in regulating the fertilizing ability spermatozoa